The Accordion Pill™, a novel gastro-retentive delivery system, significantly improves the Pharmacokinetics of drugs with either narrow absorption window or poorly soluble drugs that belong to Biopharmaceutics Classification System (BCS) class II and Class IV.
The Accordion Pill™ is designed for drugs that are characterized by one of the following:
• Narrow Absorption Window (poor colonic absorption)
• Poor solubility, BCS class II or IV
• Act locally, in the stomach or in the upper part of the GI tract
• Adverse effects correlate with the drug reaching the distal parts of the GI tract